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KMID : 0358920160430040435
Journal of the Korean Academy of Pedodontics
2016 Volume.43 No. 4 p.435 ~ p.442
Determination of Physiological Changes according to Nitrous Concentration and Application Method
Lee Daw-Woo

Han Ji-Hoon
Yang Yeon-Mi
Abstract
The aim of this study was to analyze physiological changes, clinical and subjective symptoms by different N2O concentrations and administration method. This study surveyed 65 men and women ages 19 to 35 and all subjects
were healthy volunteers, with no contraindication for use of N2O sedation. The N2O sedation was carried out in a way that increases by 10 percent to one-minute interval or increases at once the desired level. Each method was required to reach 30 or 50 percent N2O concentration. The way to gradually raise the N2O concentration can reduce the risk by decreasing the pulse reduction rate at the same N2O concentration. SpO2 has no statistical significance according to N2O concentration and method of administration. Pulse rate reduced significantly when 50% N2O increase at once during sedation and 100% O2 after 5 minutes. The way to gradually raise the N2O concentration is safe for reducing pulse rate.
KEYWORD
Nitrous oxide , Conscious sedation , Vital signs , Pulse rate , Oximetry
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